A group of ancient Greek cities along the coast of southern Italy; a general term for the Greek cities of southern Italy and Sicily. An important center of the Greek civilization, it was the site of extensive trade and commerce and the seat of the Pythagorean and Eleatic systems of philosophy. Euboeans founded the first colonies, Pithecussae and Cumae, about 750 BC, and subsequently Spartans settled at Tarentum; Achaeans at Metapontum, Sybaris, and Croton; Locrians at Locri Epizephyrii; and Chalcidians at Rhegium (Reggio di Calabria). After the 5th century, attacks by neighboring Italic peoples, strife among cities, and malaria caused most of the cities to decline in importance.